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Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 19 of 19

About the Author: Dr Sherry Bass is a Distinguished Teaching Professor at the SUNY State College of Optometry where she has been a member of the faculty for 45 years. She is an attending in the Retina and Electrodiagnostic clinic at the University Eye Center. Dr. Bass in a national

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 19 of 192025-11-06T16:54:45+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 18 of 19

About The Author: Dr. Harriette Canellos is an Associate Clinical Professor at SUNY College of Optometry, Director of the University Eye Center’s Referral Service and Instructor of Record of the Fourth Year Program.  She supervises interns and residents in the Advanced Anterior Segment Disease, Cataract and Oculoplastic clinics.Dr. Canellos is

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 18 of 192025-11-06T16:52:35+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 17 of 19

About The Author: Dr. Andrew Dohanich graduated from Massachusetts College of Pharmacy and Health Sciences in 2025. He is currently completing a residency in Primary Care at SUNY College of Optometry.

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 17 of 192025-11-06T16:51:02+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 15 of 19

References: Cirone D, Mandarà E, Simone LD, et al. Ophthalmic manifestations of cat scratch disease. Annals of Eye Science 2021;6(0):17-17.Habot-Wilner Z, Trivizki O, Goldstein M, et al. Cat-scratch disease: ocular manifestations and treatment outcome. Acta Ophthalmologica 2018;96(4):524-32.Hong H, Li T, Ying Y, et al. Cat-scratch disease manifesting as uveitis and binocular

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 15 of 192025-11-06T16:47:21+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 14 of 19

Discussion and Conclusion: Typical oral antibiotic treatment options include doxycycline, azithromycin, rifampin, and trimethoprim-sulfamethoxazole. Doxycycline is preferred due to its effective penetration of the eye. Azithromycin is recommended for children under the age of 12 as doxycycline should be avoided in this demographic. In cases of neuroretinitis, systemic corticosteroids are often

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 14 of 192025-11-06T16:45:57+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 13 of 19

Treatment and Management: Cat scratch disease does not typically require treatment as the symptoms are usually self-limited in nature. Treatment with antipyretics and warm compresses at the site of inoculation are usually sufficient for mild cases. Severe systemic findings/ocular findings warrant treatment with systemic antibiotics, as well as both topical and

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 13 of 192025-11-06T16:45:23+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 12 of 19

Diagnosis: Diagnosis of CSD can be challenging as Bartonella henselae is a fastidious organism and is difficult to culture. History of recent close contact with unvaccinated cats leads the diagnosis. Our patient had confirmed recent close contact with cats during a period of inebriation. Diagnosis of CSD is confirmed by serology

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 12 of 192025-11-06T20:35:44+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 11 of 19

Differential Diagnoses: Granulomatous Uveitis → Syphilis, Sarcoid, Tuberculosis, HerpesNeuroretinitis → Lyme Disease, Salmonella, Toxoplasmosis, ToxocariasisBilateral Optic Disc Edema → Malignant Hypertension, Intracranial Mass

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 11 of 192025-11-06T20:39:20+00:00

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 10 of 19

  Figure 5. Central 30-2 Humphrey visual fields demonstrate enlarged blind spots typically seen with optic disk edema. A cluster of field defects can be appreciated superior temporal in the right eye. The left eye demonstrates scattered, non-specific defects of the inferior field

Case #77: Atypical Bilateral Neuroretinitis and Anterior Granulomatous Uveitis Presenting as Initial Signs of Cat Scratch Disease – Page 10 of 192025-11-06T20:34:22+00:00