Pigmentary Retinopathy DDx:

Degenerative:

Age-related macular degeneration

Myopic retinopathy

 

Toxicity:

Chloroquine/Hydroxychloroquine

Phenothiazines – Thioridazine, chlorpromazine

Pentosan Polysulfate

Deferoxamine Toxicity

Vitamin A deficiency

Abetalipoproteinemia

 

Malignant Conditions:

Melanoma-associated retinopathy – Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP)

Retinal Dystrophies:

Retinitis Pigmentosa

Pattern Dystrophy

Cone-rod dystrophy

Stargardt disease

IRD in Mitochondrial disorders (Kaerns-Sayre Syndrome, Maternally inherited diabetes and deafness, Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes, Myoclonic epilepsy with ragged red fibers)

Usher Syndrome

Alstrom Syndrome

Refsum Disease

Alport Syndrome

 

Infectious + Inflammatory Causes:

Congenital Syphilis

Rubella Retinopathy

Toxoplasmosis

CMV Retinitis

Tuberculosis pigmented retinopathy