Case #74: Pentosan Polysulfate Maculopathy: Another Differential Diagnosis for Night Blindness – Page 16 of 23

Proposed Diagnostic Criteria^5,7

Barnes and colleagues

1. Macular hyperpigmented spots with yellow-orange deposits and patchy RPE atrophy on fundus photography
2. Densely packed clusters of hyper and hypoAF areas within the posterior pole on FAF
3. Focal thickening of the RPE with hyperreflectance on NIR
4. Peripapillary hypoAF halo
5. Maximum size of the hyperAF spots of 2 venule widths
6. Absence of typical drusen