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References L. Konstantinidis, I. Mantel, J-Antoine C. Pournaras et.a. Intravitreal ranibizumab (Lucentis) for the treatment of myopic choroidal neovascularization. Greafes Arch Clin Exp Ophthalmol 2009 247: 311-318 W-Mai Chan, Timothy Y, Y.Lai et al. Intravitreal Bevacizumab (Avastin) for Myopic Choroidal Neovascularization Six-Month Results of a Prospective Pilot Study. Ophthalmology 2007114:2190-2196 T.Yoshida, K. ohno-Matsui, K.
Acknowledgements Yuliya Bababekova - - - - - - - - - - - - Ines Fernandez Sanjeev Nath
Jerome Sherman, OD, FAAO Jerome Sherman, O.D., is perhaps optometry's most prolific writer, publishing over 650 clinical articles, research manuscripts, book chapters and two CDs. He is senior author of three books that were published in 2007, and has delivered over three thousand lectures both nationally and internationally. He has served as a
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What is the earliest finding in myopic staphyloma? Topcon 3D OCT:Segmentation of the RPE revealing the two mini bulges in the left eye as viewed from behind or below the eye.See Case 1-Pathological Myopia for answer
Summary of Recent Studies A small study used intravitreal bevacizumab (Avastin) on twenty- two eyes of 22 patients with CNV secondary to high myopia. Fifteen (68.2%) eyes had an improvement of 2 or more lines of visual acuity at 6 months.2 No ocular or systemic complications were noted after intravitreal injections. The 6 month outcome
Comments and Conclusions High myopia results in a substantial percentage of legal blindness in many developed countries3,4; In France it is the 5th leading cause of blindness.6 High Myopia (defined as over 8D) occurs in 27% to 33% of all myopic eyes, corresponding to a prevalence of 1.7% to 2% in the general population
Treatment Options for Choroidal Neovascularization in High Myopia Intravitreal anti-VEGF agents such as bevacizumab (Avastin) and ranibizumab (Lucentis) Laser Photocoagulation Photodynamic Therapy (PDT) with Verteporfin Intravitreal Steroid Injections Surgical Extraction of CNV Macular Translocation Various Combination Treatments
Histological Section as Compared to the OCT Image Although the photoreceptor integrity line, or the PIL (defined as the junction between the inner and outer segments) is barely visible in most histological sections, it is highly prominent in normal SD OCTs. The PIL, as shown above, should be continuous throughout the entire scan in
Some Etiologies of CNV Age-Related macular degeneration (Wet) High Myopia Presumed Ocular Histoplasmosis Syndrome (POHS) Choroidal rupture secondary to trauma Angioid Streaks Ocular Tumors Miscellaneous ocular infections and inflammations Idiopathic CNV
