Stargardt Plus Glaucoma – Page 20 of 30
RNFL measurements with Cirrus™ HD-OCT See for RNFL thickness interpretation with both GDx and OCT.
Stargardt Plus Glaucoma – Page 19 of 30
RNFL thickness measurements with Cirrus™ HD-OCT Retinal nerve fiber layer (RNFL) abnormalities can be easily documented with the Cirrus™ and are in general agreement with the degree of optic disc cupping. For example, the inferior temporal RNFL defect is in concordance with the inferior temporal notch OS.
Stargardt Plus Glaucoma – Page 18 of 30
Histological Section as Compared to the OCT Image Although the photoreceptor integrity line, or the PIL (defined as the junction between the inner and outer segments) is barely visible in most histological sections, it is highly prominent in normal SD OCTs. The PIL, as shown above, should be continuous throughout the entire scan
Stargardt Plus Glaucoma – Page 17 of 30
Topcon 3D OCT OD As we image further into the superior fundus, the RPE, the PIL and the outerlimiting membrane become somewhat discernable. Note the grossly abnormalPIL which is barely discernable in both eyes.OS
Stargardt Plus Glaucoma – Page 16 of 30
Summary Cirrus™ HD-OCT OS Note the similar findings in the left eye.
Stargardt Plus Glaucoma – Page 15 of 30
Summary Cirrus™ HD-OCT OD As anticipated, comparison of macula thickness in this case to the normative database documents that at least 99% of normal eyes have a macula which is thicker than the case presented.
Stargardt Plus Glaucoma – Page 14 of 30
Cirrus™ HD-OCT OD Bruch's membrane is well visualized in both the color and grey scale images because of the extreme attenuation of the RPE.
Stargardt Plus Glaucoma – Page 13 of 30
Cirrus™ HD-OCT OD In the image above, blood vessels cast shadows on underlying structures. OS The blue horizontal section through the fovea in the lower images reveals the extremely thin macula. Bruch's membrane is "unmasked" as the RPE is lost.
Stargardt Plus Glaucoma – Page 12 of 30
Cirrus™ HD-OCT OD The PIL is only visible in sections distant from the macula. The RPE is quite attenuated in the macula which "unmasks" the underlying Bruch's membrane. Because of the retinal thinning, choroidal vasculature is well visualized.
Stargardt Plus Glaucoma – Page 11 of 30
Optos ResMax™ green and red separation images OS Separation of the composite color optos® images into red and green channels is helpful in many cases. Subtle findings at the level of the retina (anterior to the RPE) are most obvious with the green separation and subtle findings at the level of the