Case #23 – Congenital Hypertrophy of the RPE

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Case 11: Optomap® Fundus Image Comparison of Right Eye The most important lesion to differentiate from CHRPE is malignant melanoma of the choroid. In contrast to a melanoma, hypertrophy of the RPE is flat and well demarcated.5 The melanoma is barely visible in green separation presumably because it has not broken through

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Case 11: A 35-year-old female with no symptoms presented for a routine exam. A lesion was found in the temporal periphery of the right eye which had not been present in any previous optomap® images. B-scan revealed the lesion was elevated approximately 1.75 mm. The lesion was determined to be a small early

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Case 10: Suspicious Nevus Topcon 3D OCT Images Figure A: The Topcon 3D representation of the lesion's elevation measuring about 250 microns is depicted on the left. This image is composed of the 128 horizontal slices within the green box. Figure B: One Topcon 3D OCT horizontal slice of the 128 sections

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Case 9: Optomap® Fundus Image Comparison of Right Eye Choridal nevi can also be misconstrued as a CHRPE lesion and are included in the differential diagnosis. A choroidal nevus can be differentiated from a CHRPE lesion due to the fact that a choroidal nevus is rarely jet black, has ill-defined borders, and it

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Case 8: A 66-year-old male presented with no visual complaints, BCVA 20/20 and vague history of trauma in the left eye. Note the 2 large lesions superior temporal which appear to be areas of "dark without pressure".

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Case 7: Optomap® Fundus Image Comparison of Right Eye In isolated CHRPE lesions, the Involved RPE cells are on average 1.5 to 2.0 times taller than normal.3 Most CHRPE lesions are better visualized in red separation than green separation as shown above.

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