Case #36 – Retinopathy of Prematurity(ROP)

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References G Heidary, D Vanderveen, LE Smith. 2009. Retinopathy of Prematurity: Current Concepts in Molecular Pathogenesis. Seminars in Ophthalmology, 24, 77-81. C Wu, DK Vanderveen, A Hellstrom, C Lofqvist, LEH Smith. 2010. Longitudinal Postnatal Weight Measurements for the Prediction of Retinopathy of Prematurity. Arch Ophthalmol, 128(4), 443-447. IS Mantagos, DK Vanderveen, LEH Smith.

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Jerome Sherman, OD, FAAO Jerome Sherman, O.D., is perhaps optometry's most prolific writer, publishing over 650 clinical articles, research manuscripts, book chapters and two CDs. He is senior author of three books that were published in 2007, and has delivered over three thousand lectures both nationally and internationally. He has served as a contributing

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Comments and Conclusions Cont'd • Neovascularization during phase Il is driven by hypoxia which stimulates elevated levels of vascular endothelial growth factor (VEGF).3 • Current treatment for ROP include peripheral retinal ablation with cryotherapy or laser photocoagulation and vitreoretinal surgery for retinal detachment.3 • In the CRYO-ROP study, cryotherapy successfully reduced the number of

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Comments and Conclusions • Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness.1 • The major risk factors for ROP are birth weight, gestational age, and supplemental oxygen treatment.1 • Infants with a birth weight lower than 1500g or gestational age less than 30 weeks are routinely screened for ROP. Of

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Case 1 & 2: Optomap® Magnified Color Fundus Images OS • Pattern VEPs in Case 1 revealed normal latencies and somewhat reduced amplitude to various check sizes in each eye. Potential visual acuity was estimated at 20/80 in the right eye and 20/30 in the left eye. • Visual acuity measurements in Case

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Case 1 & 2: Optomap® Color Fundus Images OS Similar findings are demonstrated in a comparison of the left eye in Case 1 and Case 2. .

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Case 1 & 2: Optomap® Color Fundus Images OD Case 1 reveals the dragged retinal vessels which is a rather common finding in ROP. Retinal vessels are more difficult to visualize in right eye of Case 2. .

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