Case #38 – Leber’s Hereditary Optic Neuropathy

Leber’s Hereditary Optic Neuropathy – Page 45 of 56

Case 2: Zeiss Stratus OCT RNFL Serial Analysis OU Note the comparison of the right eye on August 2007 (black curve) shown in the upper image and the left eye (black curve) on the same date shown in the lower image. In the right eye during the August 2007 visit, the RNFL is markedly reduced

Leber’s Hereditary Optic Neuropathy – Page 45 of 562021-05-05T20:57:51+00:00

Leber’s Hereditary Optic Neuropathy – Page 44 of 56

Case 2: Zeiss GDx Serial Analysis OU As the RNFL is attenuated in the right eye as revealed on the August 2007 visit, the RNFL on this visit in the left eye is increased in thickness.

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Leber’s Hereditary Optic Neuropathy – Page 39 of 56

Case 2: Topcon & Zeiss VISUCAM Color Fundus Camera Images & Zeiss GDx OS The GDx Advanced Serial Analysis did not reveal any major change until August 2007. Note the increased thickness was most marked inferior temporally in the left eye during this visit.

Leber’s Hereditary Optic Neuropathy – Page 39 of 562021-05-05T20:58:57+00:00

Leber’s Hereditary Optic Neuropathy – Page 38 of 56

Case 2: Topcon & Zeiss VISUCAM Color Fundus Camera Images OS Progression of disc and surrounding retinal changes OS are appreciated in August 2007. BCVA had dropped to 20/40 OS in August 2007.

Leber’s Hereditary Optic Neuropathy – Page 38 of 562021-05-05T20:59:05+00:00

Leber’s Hereditary Optic Neuropathy – Page 37 of 56

Case 2: Zeiss VISUCAM Color Fundus Camera Image & Zeiss GDx OS August 2007 By August 2007, there is observable increase in disc hyperemia, increased thickness of the RNFL and the presence of some telangiectatic or "corkscrew" vessels on and surrounding the optic disc in the OS.

Leber’s Hereditary Optic Neuropathy – Page 37 of 562021-05-05T20:59:14+00:00