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Case 1: OptoVue IVue Anterior Segment SD-OCT SD-OCT of the anterior segment using the iVue by Optovue fails to reveal elevations on the iris. The pigmented dots and small spots on the iris visible with a slit lamp are likely just small nevi or freckles and not Lisch nodules.
The patient has hundreds of flat, coffee colored lesions of various sizes on her body which represent melanin deposition. These are generally termed café-au-lait spots. A much smaller number of lesions are somewhat raised and these represent cutaneous and subcutaneous neurofibromas. Both are common in NF type 1.
Case 1 Note similar findings in the left eye as well.
Case 1 Although traditional fundus photography (top left) and Optos Color Image (top right) yield some information about the deep lesions, the Annidis MSI yields important information about the deep lesions not clearly visible before.
Case 1: Annidis MSI OU The Color Composite Image is a composite of the Green and Red1 images, useful for comparing data acquired with the Annidis MSI to standard fundus photography.
Case 1: Annidis MSI OS Actual data from the left eye of our patient with NF. Ten LEDs are used and then resulting images are displayed. The Color Composite is a pseudo color ¡mage and is based upon some of the data generated by the 10 LEDs.
Multi-Spectral Imaging (MSl) Fundus Spectral Slices This simplistic diagram demonstrates the different penetration depths of several LEDs and the various images that may result.
Annidis MSI Capturing Data The blue line highlights the near Gaussian distribution of the human eye's sensitivity to light. Traditional fundus cameras mimic this and reveal images similar to what is seen by the human eye. Blue, Red, and Green light sensors have been used in Fundus cameras. Beyond 650nm, traditional fundus imaging
Case 1: Annidis MSI OD The Annidis Multi-Spectral Imaging, of our patient with NF uses 10 different LEDs, each of a different color and somewhat different penetration range. The Green, Yellow and Amber LEDs do not penetrate well and reveal detailed information about the inner retinal structures. The Red and Infrared LEDs penetrate deeper into
Case 1: Optomap® Fluorescein Angiography Image OS
