Case #61 – Range of Retinoschisis Revisited

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Sherry J. Bass, OD Dr. Sherry Bass is a Distinguished Teaching Professor at the SUNY State College of Optometry where she has been a faculty member for over 40 years. Dr. Bass is an attending in the Retina and Electrodiagnostic Services at SUNY and also serves as the Residency Supervisor for the Residency in Ocular Disease. She is a

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Stephen A. Dellostritto, OD Stephen Dellostritto, OD is SUNY College of Optometry's combined graduate resident. His research primarily revolves around myopia and ON and OFF neural pathways and his clinical focus is in ocular disease. Dr. Dellostritto has received the Dr. William M Eisenberg Memorial Award for Excellence in Ocular Disease and was a

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Lawrence A. Yannuzzi, MD Lawrence A. Yannuzzi, MD is a graduate of Harvard College and Boston University Medical School, where he was honored as a distinguished alumnus. He is the professor of clinical ophthalmology at Columbia University Medical School; vice-chairman and director of the Retinal Research Center of the Manhattan Eye, Ear &

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Special  AcknowledgementK. Bailey Freund, MD  Bailey Freund, MD is a retina specialist who practices at Vitreous-Retina-Macula Consultants of New York. He is a graduate of Williams College and the New York University School of Medicine. Dr. Freund’s residency training in general ophthalmology and two-year fellowship in medical and surgical retina were at the Manhattan

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Jerome Sherman, OD, FAAO Dr. Sherman is a graduate of Pennsylvania College of Optometry and currently holds the position of Distinguished Teaching Professor at the State University of New York and Schnurmacher Institute of Vision Research. His private sector experience includes clinical care and research at the Eye Institute and Laser Center and more recently

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REFERENCES  Molday, Robert S et al. “X-linked juvenile retinoschisis: clinical diagnosis, genetic analysis, and molecular mechanisms.” Progress in retinal and eye research vol. 31,3 (2012): 195-212. doi:10.1016/j.preteyeres.2011.12.002Renner, Agnes B et al. “ERG variability in X-linked congenital retinoschisis patients with mutations in the RS1 gene and the diagnostic importance of fundus autofluorescence and OCT.”

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COMMENTS        Stephen A. Dellostritto, OD  The funduscopic appearance and structural changes in patients with stellate non-hereditary idiopathic foveomacular retinoschisis (SNIFR) and congenital X-linked retinoschisis (XLRS) are grossly similar. The primary differences between the two conditions lie in the genetics and the functionality of the retina based on ERG interpretation. XLRS is associated with an

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