Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 6 of 16

Exam Continued Gonioscopy was open to ciliary body with 2+ pigment in all quadrants of both eyes and a concave iris approach.Examination of the lens revealed dense pigment deposition on the posterior capsules of both lenses.Intraocular pressure was 17mmHg OD and 18mmHg OS.Dilated fundus examination revealed an intact retina and clear

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 6 of 162025-02-04T18:05:06+00:00

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 4 of 16

Initial Presentation A 45 year old male presents complaining of decreased vision since childhood.BCVA: 20/60 OD/OS.Refractive Error:OD: -8.00 -2.00 x 135OS: -8.00 -1.25 x 020Externals: Normal OD/OS.Slit Lamp revealed mid-peripheral iris transillumination defects 360 in both eyes and pigment on the corneal endothelium.

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 4 of 162025-02-04T18:01:47+00:00

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 3 of 16

Clinical Signs The classic clinical signs of PDS include midperipheral iris transillumintation defects and pigment deposition on the corneal endothelium, referred to as Krukenberg's spindle.The angle usually appears densely pigmented on gonioscopy.More rarely, there can be pigment deposition seen on the anterior and posterior lens capsule.The present case discusses an incidence

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 3 of 162025-02-04T18:00:15+00:00

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 2 of 16

Pigment Dispersion Syndrome (PDS) A condition in which pigment from the iris is released within the anterior chamberPigment can migrate to the angle and cause increased intraocular pressure by decreasing aqueous outflowThere is an estimated 30-50% chance of patients with PDS to develop pigmentary glaucoma in their lifetime.

Case #73: Atypical Presentation of Pigmentary Dispersion Syndrome – Page 2 of 162025-02-04T17:58:04+00:00