Comments and Conclusions

• Sickle cell is one of the most common genetic disorders encountered clinically and has myriad retinal presentations.
• A central retinal artery occlusion in a sickle cell anemia (SS) or sickle cell disease (SC) patient may be due to dehydration6 such as in this case.
• If diagnosed early, blood transfusion6 and Tissue Plasminogen Activator (TPA)7 occasionally may be helpful.
• Asymptomatic black and Hispanic patients without a history of Sickle Cell who present with characteristic peripheral retinal findings should be worked up for sickle cell.
• Timely diagnosis and treatment of Proliferative Sickle Cell Retinopathy may prevent vitreal hemorrhages, traction retinal detachment and blindness.