Introduction to iWellness Exam

Results: Of the CNs, 104 of 105 were identified as normal (Specificity =99%). Of the CDs, 97 of 102 were properly identified with retinal and/or ON disease (sorted as category 2, 3, or 4), 63 of 68 of the retinal pathology subjects were detected (sorted as category 2 or 4), and 45 of the 50 ON pathology subjects were detected (sorted as category 3 or 4), (Sensitivity of 95%, 93%, and 90%. respectively). None of the Category 2 subjects were mis-sorted as Category 3, and none of the Category 3 subjects were mis-sorted as Category 2.

Conclusions: The iWellnessExam screening protocol provides data for the efficient, effective identification of both retinal and ON pathology, with high specificity and sensitivity when reviewed by a well-trained eye care clinician. It would be valuable to repeat the study with a novice and/or student clinician reviewing the same data set to ascertain inter-observer variability, as well as the impact of clinical experience on accurate referral, based on the screening data.