Neurofibromatosis (NF)

• Neurofibromatosis (NF) is one of the 10 most common genetic disorders known to mankind.1
• NF is the most common single gene Mendelian disorder with visual implications.
• Common ophthalmic findings in NF include Lisch nodules and optic nerve or visual pathway gliomas.
• Choroidal lesions are rarely mentioned In the world’s NF literature.
• Here we present a remarkable NF case with dozens of choroidal lesions which are virtually invisible to ophthalmoscopy, 78 D lens examination and standard tundus photography.
• In contrast, these choroidal lesions are extremely well documented with a new form of fundus documentation termed Multi-Spectral lmaging (MSI).