When a RNFL loss is not due to Glaucoma

V – vascular
I – infectious
T – trauma
A – autoimmune
M – metabolic
I – inherited
N – neurodegenerative
E – endocrine
S – senile

V – vitamin deficiency
I – inflammatory
T – toxic
A – allergic
M – mass lesions
I – idiopathic
N – nutritional
E – environmental
S – stress

Figure : VITAMINESx2
Once glaucoma has been ruled out, this mnemonic is helpful to remember other possible etiologies of RNFL loss in non-glaucomatous optic nerve disorders. See details in: The Retinal Nerve Fiber Layer in Clinical Practice.