Images reveal abnormal responses as seen in this patient with early Plaquenil toxicity. Although the patient has no symptoms, 20/20 VA, and unremarkable fundus findings, mfERGs document functional retinal abnormalities. The mfERGs are abnormal centrally OU. In contrast to the normative database, the entire central response is reduced and depicted in dark blue in the images below. The color code reveals that the dark blue center corresponds to about a 4 standard deviation reduction in amplitude as compared to the normative database.