Summary and Conclusions

  • PAF allows 200 degrees of the fundus to be imaged without dilation in a single 250 msec flash.
  • PAF documents the integrity of the RPE (and overlying photoreceptors) throughout the entire image.
  • PAF abnormalities occur in myriad retinal disorders including a spectrum of retinal degenerations, as presented in this part I of RR54.
  • No other technology—including OCT and BIO—is capable of providing this level of assessment of the RPE.
  • PAF reveals abnormalities often invisible to ophthalmoscopy.
  • Part Il of RR 54 will demonstrate some cases of retinal degeneration essentially invisible to ophthalmoscopy but dramatically abnormal with AF.
  • Additional studies are required to determine the clinical significance of these remarkable images.