Early Detection of Stargardt Disease with OCT and AF – Page 8 of 30

Both the AF images and the OCTs reveal marked abnormalities in the outer retina of both eyes. AF-hyper and later
hypo findings suggest a primary abnormality of the RPE and secondary involvement of the overlying photoreceptors.
Stargardt’s disease with fundus flavimaculatus is the probable diagnosis of the son. Flash ERGs were obtained and
were low normal in amplitude and not delayed under photopic and scotopic conditions in both eyes. Such normal or
near normal ERGs effectively rule out an overall cone-rod dystrophy.