Leber’s Hereditary Optic Neuropathy – Page 23 of 56

The maia™ was repeated 24 days after the initial visit (two weeks after the initiation of treatment). Note the sensitivity of many points decreased significantly corresponding to the red dots in the right eye. The numbers correspond to the change in dB sensitivity over time. The white dots correspond to points that did not change in sensitivity, therefore, have an associated zero dB change over time. The four points depicted in green correspond to points where sensitivity increased, but the associated dB values are not statistically significant.