Follow-up and Implications to the Eye Clinician

  • Although our patient has no neurological symptoms, a comprehensive neural evaluation has been initiated. Genetic testing will also be obtained2-9

  • Neurological disorders may result in loss of retinal tissue.
  • RNFL thinning in a glaucoma suspect may not be due to glaucoma but to an unrelated neurological disorder.
  • As this case suggests, loss of retinal tissue including the RNFL may occur in a patient with an undiagnosed neurological disorder.
  • Fortunately, the pattern of RNFL loss may be helpful in the differential diagnosis.
  • Temporal loss of RNFL, such as In this case, is unusual in glaucoma.
  • Examples of RNFL loss in the non-glaucomatous optic neuropathies are included in: