Macular Pigment Following Supplement of All Three Carotenoids
(MOST Study)
- Results: There was a significant increase in serum concentrations of MZ and L after two weeks of supplementation (p < 0.05). Four subjects (one normal and three AMD) who had an atypical MPOD spatial profile at baseline had the more typical MPOD spatial profile (i.e., highestMPOD at the center) after eight weeks of supplementation.
- Conclusion: We report significant increases in serum concentrations of MZ and L following supplementation with MZ, and Z and a significant increase in MPOD, including its spatial profile, after two weeks of supplementation. Also, this study has detected the possible presence of MZ in human serum pre-supplementation and the ability of the study carotenoid formulation to rebuild centralMPOD in subjects who have atypical profiles at baseline.
