Cirrus™ HD-OCT Horizontal Scan Image of Normal Control OD

Although the retinal pigment epithelium (RPE) is only a single layer of cells, it appears as two reflective layers with a dark zone in between on high definition OCT scans. The “inner reflection” has been referred to by some authors as the outer segment-RPE interdigitation (OS/RPE)1 or Verhoeff’s membrane2. The outer reflection is the RPE/Bruch’s membrane complex (RPE/BM).1 Note the two reflections from the RPE complex are only visible on high definition scans. On lower resolution OCT scans the RPE generally appears as one solid thick band.