OCT Reference/Normative Database
Exclusion criteria for the different OCT companies studies for their normative database.9
With each OCT scan, the result is compared to that specific company’s normative database. These databases were created by each company’s studies of “normal” individuals. Each company had a specific inclusion and exclusion criteria for those that would be incorporated in the normative database. Although some of these companies did have a wide range of myopic individuals, the actual representation of most participants was located towards the mean of the refractive error. This heightens the difficulty of diagnosing glaucoma in highly myopic patients as the OCT scan of a highly myopic patient is not likely compared to other healthy highly myopic individuals. Studies have shown that using a myopic normative database improves the specificity without compromising the sensitivity when compared to current OCT normative databases.10