Macuscope

  • The macular protective pigment density (MPPD) refers to macular protective pigment layer composed of the carotenoids: lutein, zeaxanthin and meso-zeaxanthin in the macula, which is anterior to, and independent of the melanin rich retinal pigment epithelium
  • Although the exact mechanism of AMD has yet to be determined, two very strong theories for its pathogenesis have come to the forefront: oxidative stress from cumulative blue light damage and reactive oxygen species (ROS) damage.
  • The eye is particularly vulnerable to blue light damage, also known as high energy visible light (HEV). HEV encompasses light from 400 nm to 500 nm.