Comments and Conclusions (con’t)
- In one study, no stage 1 lesions with posterior vitreous separation from the macula progressed to full thickness holes.4
- In the same study, 47 out of 365 patients or 13% had a 4-year risk of developing a macular hole in the fellow eye.4
- Most Stage 2 lesions enlarge and VA decreases.6
- Conditions such as branch retinal vein occlusion9, and accidental laser burns8 have been described in association with macular holes.4
- The concept of lysing the vitreoretinal juncture and core vitreous has been described as pharmacologic vitreolysis.1
- Pharmacologic vitreolysis is an emerging therapeutic modality intended to lessen the severity of PVD by chemically altering the vitreous structure and weakening vitreoretinal adhesion in order to safely detach the vitreous in a benign fashion.1