References: Augsburger J.J., Correa Z.M., Trichopoulos N., Shaikh A. Size Overlap between benign melanocytic choroidal nevi and choroidal malignant melanomas. Investigative Ophthalmology and Visual Science 2008; 49 (7): 2823-2827 Abramson, D. (Personal communication, May 2009) Shields C.L. The hunt for the secrets of uveal melanoma. Clinical and Experimental Ophthalmology 2008; 36:277-280 Shields C.L., Shields J.A.,
Special Acknowledgements David Abramson Yuliya Bababekova Ines Fernandez Sanjeev Nath
Jerome Sherman, OD, FAAO Jerome Sherman, O.D., is perhaps optometry's most prolific writer, publishing over 650 clinical articles, research manuscripts, book chapters and two CDs. He is senior author of three books that were published in 2007, and has delivered over three thousand lectures both nationally and internationally. He has served as a contributing editor
The following is a list of links to the companies and contributors of the Indeterminate Melanocytic Choroidal Tumor Case Study : http://www.lulu.com/content/hardcover-book/photoreceptor-integrity-line-as-revealed-by-spectral-domain-oct/5738467
All therapeutic interventions have risks. Above are many of the known risks of chemotherapy and radiation as documented by Dr. David Abramson.
Treatment for Metastatic Uveal Melanoma? Many of us have seen one or more patients with uveal melanoma, a condition which is virtually a death sentence if it metastasizes as is often the case. In the past decade. Memorial Sloan-Kettering Cancer Center in NY has greatly expanded its ophthalmic oncology division and has just announced
Disposition and Follow Up • In consultation with David Abramson, Chief of Ophthalmic Oncology at Memorial Sloan-Kettering Cancer Center in NY, the decision in this case was to follow the patient every three months without intervention.2 • Follow-up includes fundus photography, and spectral domain OCT, panoramic imaging with optomap® (including analysis of red and
Risk Factors for Choroidal Melanoma Light eye color3 Fair skin3 Inability to tan3 Tumor thickness greater than 2 mm Presence of subretinal fluid1 Orange pigment4 Tumor margin within 3 mm of the disc4 Monosomy of chromosome 33
Histological Section as Comapred to the OCT Image Although the photoreceptor integrity line, or the PIL (defined as the junction between the inner and outer segments) is barely visible in most histological sections, it is highly prominent in normal SD OCTs. The PIL, as shown above, should be continuous throughout the entire scan in
Note that this lesion, presumably a nevus, is obvious with red laser separation but disappears with green separation.