Case #49 – Central retinal artery occlusion in sickle cell anemia

Central retinal artery occlusion in sickle cell anemia – Page 35 of 35

References1. Appen, RE SH Wray, and DG Cogan. “Central Retinal Artery Occlusion.” American Journal of Ophthalmology 79.3 (1975): 347-81. Print.2. Asdourian, G., K. C. Nagpal, M. Goldbaum, D. Patrianakos, M.F. Goldberg, and M. Rabb. “Eyolution of the Retinal Black Sunburst In Sickling Haemoglobinopathies.” British Journal of Ophthalmology 59.12 (1975): 710-16. Print.3. Justice, Johnny, and Robert

Central retinal artery occlusion in sickle cell anemia – Page 35 of 352023-02-02T20:27:29+00:00

Central retinal artery occlusion in sickle cell anemia – Page 33 of 35

Jerome Sherman, OD, FAAO Jerome Sherman, O.D., is perhaps optometry's most prolific writer, publishing over 650 clinical articles, research manuscripts, book chapters and two CDs. He is senior author of three books that were published in 2007, and has delivered over three thousand lectures both nationally and internationally. He has served as a

Central retinal artery occlusion in sickle cell anemia – Page 33 of 352023-02-02T20:27:30+00:00

Central retinal artery occlusion in sickle cell anemia – Page 31 of 35

Comments and Conclusions • Sickle cell is one of the most common genetic disorders encountered clinically and has myriad retinal presentations. • A central retinal artery occlusion in a sickle cell anemia (SS) or sickle cell disease (SC) patient may be due to dehydration6 such as in this case. • If diagnosed early, blood transfusion6

Central retinal artery occlusion in sickle cell anemia – Page 31 of 352023-02-02T20:27:30+00:00

Central retinal artery occlusion in sickle cell anemia – Page 30 of 35

Differential Diagnosis? (from RR #29) • Proliferative Sickle Cell Retinopathy (PSR) OD>OS • Proliferative Diabetic Retinopathy • PDR: (typically mid-peripheral and posterior pole, has to be DM (+)) • BRVO/CRVO: (no signs of it, no associated systemic diseases, young patient) • ROP: (patient is a normal term baby) • FamilIal Exudative Vitreoretinopathy: (no

Central retinal artery occlusion in sickle cell anemia – Page 30 of 352023-02-02T20:27:31+00:00

Central retinal artery occlusion in sickle cell anemia – Page 27 of 35

Case 2: Optomap® Fundus Image Comparisons of Right Eye Multiple peripheral vascular occlusions lead to hypoxic events that trigger growth of new vessels in a "seafan" pattern. Later stages result in fibrovascular proliferation.

Central retinal artery occlusion in sickle cell anemia – Page 27 of 352023-02-02T20:27:31+00:00