Case #49 – Central retinal artery occlusion in sickle cell anemia

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References1. Appen, RE SH Wray, and DG Cogan. “Central Retinal Artery Occlusion.” American Journal of Ophthalmology 79.3 (1975): 347-81. Print.2. Asdourian, G., K. C. Nagpal, M. Goldbaum, D. Patrianakos, M.F. Goldberg, and M. Rabb. “Eyolution of the Retinal Black Sunburst In Sickling Haemoglobinopathies.” British Journal of Ophthalmology 59.12 (1975): 710-16. Print.3. Justice, Johnny, and Robert

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Jerome Sherman, OD, FAAO Jerome Sherman, O.D., is perhaps optometry's most prolific writer, publishing over 650 clinical articles, research manuscripts, book chapters and two CDs. He is senior author of three books that were published in 2007, and has delivered over three thousand lectures both nationally and internationally. He has served as a

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Comments and Conclusions • Sickle cell is one of the most common genetic disorders encountered clinically and has myriad retinal presentations. • A central retinal artery occlusion in a sickle cell anemia (SS) or sickle cell disease (SC) patient may be due to dehydration6 such as in this case. • If diagnosed early, blood transfusion6

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Differential Diagnosis? (from RR #29) • Proliferative Sickle Cell Retinopathy (PSR) OD>OS • Proliferative Diabetic Retinopathy • PDR: (typically mid-peripheral and posterior pole, has to be DM (+)) • BRVO/CRVO: (no signs of it, no associated systemic diseases, young patient) • ROP: (patient is a normal term baby) • FamilIal Exudative Vitreoretinopathy: (no

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Case 2: Optomap® Fundus Image Comparisons of Right Eye Multiple peripheral vascular occlusions lead to hypoxic events that trigger growth of new vessels in a "seafan" pattern. Later stages result in fibrovascular proliferation.

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