Case #23 – Congenital Hypertrophy of the RPE

Histological Section as Compared to the OCT Image  Although the photoreceptor integrity line, or PIL (defined as the junction between the inner and outer segments) is barely visible in most histological sections, it is highly prominent in normal SD OCTs. The PIL, as shown above, should be continuous throughout the entire scan in

Case 2: Topcon 3D OCT Images of Right Eye

Case 2: Isolated CHRPE Lesion Topcon Undilated Fundus Image of Right Eye Case 2: A 26-year-old asymptomatic Asian female with BCVA 20/20 OU. Note the pigmented lesion located superior temporal to the disc.

Case 1: Heidelberg Engineering SPECTRALIS® OCT Images of Right Eye

Case 1: Optomap® Images and Heidelberg Engineering SPECTRALIS® OCT of Right Eye The vertical OCT sections are through the large lesion in the nasal periphery of the right eye shown on the previous page. It appears that the retina is elevated possibly due to an underlying choroidal lesion such as a nevus

Case 1: Optomap® Fundus Image Comparison of Right Eye The pigmented lesions are easily discerned in the composite color (top) and red separation (bottom) optomap® images, but not in the green separation (middle) optomap® image. Since the large lesion is not visible in green separation, it is possible the lesion is under the RPE and

Congenital grouped pigmentation of the RPE are grouped in clusters often in a single quadrant of the retina.1 The lesions are often larger in the periphery and decrease in size closer to the disc.2 The smaller lesions are often paired which resemble animal tracks.

Case 1: Optomap® Color Fundus Image of Right Eye

Note the area of white without pressure in the temporal periphery of the right eye.