Case #48 – CORDA-Enhanced SD-OCT Improves RNFL Analysis

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¡Vue ¡WellnessExam OD Using the iWellnessExam program, a single 2 second scan yields 8 high resolution cross sections as well as the Inner Retina Thickness (or GCC) Map. Note that the Full Retina Thickness Map is 7mm x 7mm.

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RTVue Inner vs Outer Retinal Thickness Accurate segmentation of the inner and outer retinal layers is supported by the devastating impact to the inner retina. which suffered an arterial occlusion, and the relative sparing of the outer retina, which receives its vascular supply primarily from the choroid.

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RTVue Inner Retinal Thickness RTVue can measure the inner retinal thickness (equivalent to the GCC) as well. Note the dramatic decrease in thickness of the inner, inferior retina as depicted in blue. Since the inferior branch of the CRA supplies the Inner retina only, this finding is anticipated.

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Introduction to GCC Map The GCC map for a normal eye shows a bright circular band surrounding the macula representing a thick GCC from healthy ganglion cells (figure A). The center of the macula is thinner because there are no ganglion cells In this area. In glaucoma, as the ganglion cells are lost, the GCC

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RTVue Outer Retinal Thickness With the Optovue RTVue, we can measure the thickness of the outer retinal layers. Note that the thickness map is essentially normal as depicted by the primarily green thickness map.

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Introduction to GCC Excerpt from “Direct Ganglion Cell Assessment with the RTVue by Optovue: The Ganglion Cell Complex Analysis” by Mike Sinai, Ph.D. Retinal ganglion cells encompass three layers In the retina: 1) the retinal nerve fiber layer (RNFL) is made up of the ganglIon cell axons. 2) the ganglion cell layer (GCL) Is

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Zeiss GDx vs Zeiss Cirrus- Comparison of Three Examinations OD Although the (clrcumpapillary) GDx RNFL does demonstrate a dramatic change and loss inferiorly. the Cirrus (circumpapillary) RNFL is essentially normal following the inferior artery occlusion. Note that GDx Is measuring the polarization or birefringence of the RNF1. but the OCT is measuring optical reflectivity.

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