Case #48 – CORDA-Enhanced SD-OCT Improves RNFL Analysis

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 21 of 35

The graph represents a pair of HR2 and LRI values for each of 36 normal subjects and 31 glaucoma subjects. HR2 pixels (or dots) show a high positive correlation with the RNFL thickness. The low correlation between LRI dots and the RNFL thickness likely denotes the lack of relatioriship between those components (i.e.

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 21 of 352021-12-01T15:36:55+00:00

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 20 of 35

Introduction to CORDA (COlor Reflectivity Discretization Analysis) CORDA software was designed to prevent the repetitive error or oversight highlighted above. it can be used to differentiate the several components of the RNFL. The software performs a discretization” analysis of the Images to quantify the number of pixels in each

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 20 of 352021-12-01T15:36:49+00:00

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 19 of 35

So why Is the RNFL normal Inferiorly with SD OCT when GDx, GCC and mala MP confirm the loss?? SD OCT measures the optical reflectivity of the entire RNFL which includes the axons, blood vessels and gilal tissue. If we can measure Just the axons (and ignore the vessels

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 19 of 352021-12-01T15:36:42+00:00

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 18 of 35

GDx, iVue GCC, and maia MP Comparison Structure-Function concordance is undeniable as demonstrated here with GDx and with GCC for structure and with maia microperimetry for function. These 3 findings belie the normar circumpapillary OCT results. Although the GDx is a circumpapipillary measurement and both mala fields and the GCC are centered around the fovea,

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 18 of 352021-12-01T15:36:32+00:00

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 17 of 35

Closure of the Inferior Branch of the Central Retinal Artery OD Fundus photo OD at To. Microperimetry (MP) with mala (using program similar to traditional 10-2) at T0 +6 mos. Optovue iVue inner retinal thickness (same as Ganglion Cell Complex GCC)atTo+6 mos. Note the remarkable sImilarity of

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 17 of 352021-12-01T15:36:23+00:00

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 16 of 35

¡Vue ¡WellnessExam OU The vertical scan of the OD (above left) demonstrates the attenuated inner retina interiorly. The Inner Retinal Thickness Table demonstrates a 47 p difference in the thickness of the superior vs inferior retina in the OD and only a 2.5 p difference in the OS. There is also more than

CORDA-Enhanced SD-OCT Improves RNFL Analysis – Page 16 of 352021-12-01T15:36:15+00:00