Case #29 – Proliferative Sickle Cell Retinopathy (PSR)

Proliferative Sickle Cell Retinopathy (PSR) – Page 4 of 34

Note the sunburst lesion (black circle) and fibroglial tissue with possible surface neovascularization (green circle) in the temporal periphery. There is also an apparent border of dark without pressure (red arrows) extending nasal to superior nasal.

Proliferative Sickle Cell Retinopathy (PSR) – Page 4 of 342021-03-10T21:54:59+00:00

Proliferative Sickle Cell Retinopathy (PSR) – Page 3 of 34

History/Chief Complaint A 27-year-old black female presented for a retinal consult. She had previously been diagnosed with sickle cell SC disease, but was lost to follow-up for one year. The patient was completely asymptomatic both visually and systemically. Clinical Findings BCVA 20/20 OU Rx: -1.25 sph OD -1.25 sph OS IOP: 14 OD 14 OS

Proliferative Sickle Cell Retinopathy (PSR) – Page 3 of 342021-03-10T21:55:08+00:00

Proliferative Sickle Cell Retinopathy (PSR) – Page 1 of 34

Sickle cell disease is one of the most common genetic diseases worldwide. Sickle cell C disease (SC) is less severe than sickle cell anemia disease (SS) and often patients are asymptomatic and unaware they have SC.1-5 43% of SC patients develop proliferative sickle cell retinopathy (PSR) and without treatment 10% of these patients will

Proliferative Sickle Cell Retinopathy (PSR) – Page 1 of 342021-03-10T21:55:24+00:00