Case #27 – Mac Degen in 2010

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Annidis Health Systems: The RHA (Early stage RPE disruption) OS: Distinct perimacular RPE disruption and RPE clumping (arrows) is most visible using the infrared image data compared to color and other wavelengths. Bottom right shows magnified area of RPE disruption seen in the infrared image. Taken together, the image data from the Annidis RHA

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Early stage RPE disruption History/ Chief Complaint 36-year-old female presented for a routine eye exam with complaints of eyestrain when using the computer. She is on the computer for 6-7 hours daily. She has also had weekly migraines for the last four years. Medications: synthroid and liquigel qhs for

Mac Degen in 2010 – Page 42 of 622021-03-03T21:01:03+00:00

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Annidis Health Systems: The RHA (Early Atrophic Macula) The oxy/deoxy hemoglobin data map generated by the Annidis RHA software (right) assists in estimating areas of vascular perfusion. White color (right) suggests perfused areas.

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Annidis Health Systems: The RHA (Early Atrophic Macula) Enhanced visualization of RPE disruption using longer wavelengths of light with the Annidis RHA. Supplements and regular monitoring of macular health were prescribed. Color composite of fundus contrasted to images generated by red, deep red and infrared wavelengths. RPE disruption (arrows) clearly distinguishable in

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Annidis Health Systems: The RHA (Early Atrophic Macula) The Annidis RHA Multi-Spectral Ophthalmoscope allows enhanced visualization of early pathological features and anatomical abnormalities. Various wavelengths of light enable the progressive examination of different depths in a 45° field of view of the retina and can aid in detecting features beyond a typical fundus camera.

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Early Atrophic Macula History 40-year-old female presented with a family history of age-related macular degeneration, but no reported vision loss. Clinical Findings BCVA: 20/20 OD/OS Normal Contrast Sensitivity (Continuous Text Low Contrast Chart by Eschenbach) Anterior segment normal in both eyes, PERRLA negative APD Soft drusen detected OD with the

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Annidis Health Systems: The RHA The RHA is a Multi-spectral digital ophthalmoscope generating spectral image data (from blue to deep IR) and data maps including 3D Stereo, color, and oxy/deoxy maps which facilitate visualization of the retina, the vitreo-macular interface and the deep choroid. *The Annidis RHA is currently available for sale in

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Advance AMD Case 3 is an example of advanced AMD with a neovascular web. The choroidal neovascularization appears more contrasted in the MAIA image and the Expert Test findings indicate progressive loss of function and a breakdown in fixation: Average Threshold is 15.9 dB; Fixation Stability

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Intermediate AMD Case 2 is an example of intermediate AMD with significant loss of the retinal pigment epithelium (RPE). The MAIA image shows what appears to be multiple soft drusen along with the RPE loss. The Expert Test describes increased functional loss compared to

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Early AMD The MAIA's infrared imaging provides a detailed visualization of the retinal morphology. The Expert Test shows that even in the early stages of AMD retinal function has been compromised. The Average threshold for this patient was 25.1 dB, which compared to the reference database of norrnal individuals,

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