Case #44 – Dots, Spots, and Other White Retinal Lesions

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Case 11: Topcon Fundus Images OS A 65-year-old white male presented with BCVA of 20/20 OU. The patient was referred because of two macroaneurysms near the macula OS. Both macroaneurysms were treated with laser and patient was returning for follow-up. Note the circinate ring of exudates surrounding the macroaneurysm superior temporal to the

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Case 10: Topcon 3D OCT Raster Scan Images SD-OCT reveals a discontinuous PIL and pigment migration corresponding to the pisciform yellow deposits (red circles). The macula was extremely attenuated and several retinal layers were missing. The missing/attenuated RPE in the macula unmasks Brush's membrane which is typically not easily visualized in OCT cross-sections.

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Case 10: Topcon Fundus Images OU A 54-year-old white male presented with BCVA of 20/400 OU. The fundus image reveals macular lesions in both eyes and pisciform pale yellow deposits throughout the posterior pole. Stargardt macula dystrophy is the most probable diagnosis. Genetic testing was recommended. For more about Stargardt see Retina Revealed: Case #

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Case 9: Topcon 3D OCT Raster Scan Images SD-OCT revealed the macular scars in both eyes as large dome-shaped hyperreflective elevations. Note the dropout of the PIL as it approaches the macula both temporally and nasally. The patient was diagnosed with Best's Disease. Genetic testing and EOGs were recommended.

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Case 9: Topcon Fundus Images OU A 77-year-old white male presented with longstanding reduced vision for the past 22 years with BCVA of 20/200 OU. Family history revealed his mother had been diagnosed with Best's Disease. The fundus images reveal well circumscribed macular scars in both eyes.

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Drusen: Clinical Features Three types of drusen: Hard drusen (cuticular or infiltrative): • Small, Yellow-White deposits of lipid-rich material • Typically 50-75 µm in size • Location: between RPE and Bruch's Subretinal drusenoid deposits*: • Drusenoid-material, similar to drusen in appearance • Size 50-75 µm • Location: subretinal between RPE

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